06.01.2012 11.Tewet. 5772
Scientists use mice with type 1 diabetes that actually develop MS; breakthrough could lead to better treatments.
All laboratory research on multiple sclerosis have been conducted until now using experimental autoimmune encephalomyelitis (EAE) as mouse model, even though it is not the same as MS. Mice with EAE – a scientific model first created in the 1920s – are raised by injecting the rodents with protein from myelin – the insulating material on the nerves that breaks down and in humans causes the disease. The myelin is then mixed with bacteria.
The mouse’s immune system attacks the myelin and produces an autoimmune-like response, which causes the disease in humans, but as bacteria are not involved in the debilitating neurological disease MS, it is not the same mechanism….